Transformation of lymphocytes from animals sensitized to Trichinella spiralis.
نویسندگان
چکیده
منابع مشابه
Specific release of neutrophillic- and eosinophilic-stimulating factors from sensitized lymphocytes.
Mitogen-stimulated lymphocytes recently have been shown to release colony-stimulating activity (CSA), a stimulator of granulopoiesis in vitro. Whether CSA release is a result of specific antigen-lymphocyte interactions has been investigated by determining the ability of spleen lymphocytes isolated from Trichinella spiralis and Bacille Calmette Guerin (BCG) infected mice to release CSA. Lymphocy...
متن کاملTrichinella spiralis: phospholipase in sensitized mice after challenge.
LARSH, JOHN E., JR., OTTOLENGHI, ATHOS, AND WEATHERLY, NORMAN F. 1975. Trichinella spiralis: Phospholipase in sensitized mice after challenge. Experimental Parasitology 37, 233-238. Mice given three sensitizing infections with Trichinella spiralis and then challenged with 400 larvae showed greatly elevated phospholipase B levels in the small intestine from one through 20 days after challenge; b...
متن کاملAmelioration of Myogenin, Bcl-2 expression and DNA damages in myocytes of Trichinella spiralis-infected mice after immunization with gamma radiation-attenuated larvae
Background: In trichinosis, the presence of muscle larvae inside skeletal striated muscle causes loss of identity and function of myotube through the releasing of myogenin and myosin. Considering the dominant role of vaccination, research on gamma radiation-attenuated vaccine has very promising value. The goal of this study was to determine the efficacy of vaccination with radiation-attenuated ...
متن کاملEvaluation of two PCR-based techniques for molecular epidemiology in Finland, a high-endemic area with four sympatric Trichinella species.
Trichinella larvae collected from wildlife, domestic and synanthropic animals in Finland were identified to species by two molecular techniques: Random amplified polymorphic DNA (RAPD) polymerase chain reaction (PCR) and the recently described multiplex PCR. The RAPD-PCR was very sensitive to the sub-optimal preservation muscle larvae and resulting in weak and smeared bands on the gels for such...
متن کاملTrichinella spiralis Calreticulin Binds Human Complement C1q As an Immune Evasion Strategy
As a multicellular parasitic nematode, Trichinella spiralis regulates host immune responses by producing a variety of immunomodulatory molecules to escape from host immune attack, but the mechanisms underlying the immune evasion are not well understood. Here, we identified that T. spiralis calreticulin (Ts-CRT), a Ca2+-binding protein, facilitated T. spiralis immune evasion by interacting with ...
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ورودعنوان ژورنال:
- Journal of immunology
دوره 107 5 شماره
صفحات -
تاریخ انتشار 1971